组织病理学图像提供了癌症诊断的明确来源，其中包含病理学家用来识别和分类恶性疾病的信息，并指导治疗选择。这些图像包含大量信息，其中大部分目前不可用人类的解释。有监督的深度学习方法对于分类任务非常有力，但它们本质上受注释的成本和质量限制。因此，我们开发了组织形态表型学习，这是一种无监督的方法，它不需要注释，并且通过小图像瓷砖中的歧视性图像特征的自我发现进行操作。瓷砖分为形态上相似的簇，这些簇似乎代表了自然选择下出现的肿瘤生长的复发模式。这些簇具有不同的特征，可以使用正交方法识别。应用于肺癌组织，我们表明它们与患者的结局紧密保持一致，组织病理学识别的肿瘤类型和生长模式以及免疫表型的转录组度量。

The fifth generation of the Radio Access Network (RAN) has brought new services, technologies, and paradigms with the corresponding societal benefits. However, the energy consumption of 5G networks is today a concern. In recent years, the design of new methods for decreasing the RAN power consumption has attracted interest from both the research community and standardization bodies, and many energy savings solutions have been proposed. However, there is still a need to understand the power consumption behavior of state-ofthe-art base station architectures, such as multi-carrier active antenna units (AAUs), as well as the impact of different network parameters. In this paper, we present a power consumption model for 5G AAUs based on artificial neural networks. We demonstrate that this model achieves good estimation performance, and it is able to capture the benefits of energy saving when dealing with the complexity of multi-carrier base stations architectures. Importantly, multiple experiments are carried out to show the advantage of designing a general model able to capture the power consumption behaviors of different types of AAUs. Finally, we provide an analysis of the model scalability and the training data requirements.

Accomplishing safe and efficient driving is one of the predominant challenges in the controller design of connected automated vehicles (CAVs). It is often more convenient to address these goals separately and integrate the resulting controllers. In this study, we propose a controller integration scheme to fuse performance-based controllers and safety-oriented controllers safely for the longitudinal motion of a CAV. The resulting structure is compatible with a large class of controllers, and offers flexibility to design each controller individually without affecting the performance of the others. We implement the proposed safe integration scheme on a connected automated truck using an optimal-in-energy controller and a safety-oriented connected cruise controller. We validate the premise of the safe integration through experiments with a full-scale truck in two scenarios: a controlled experiment on a test track and a real-world experiment on a public highway. In both scenarios, we achieve energy efficient driving without violating safety.

We study the learning dynamics of self-predictive learning for reinforcement learning, a family of algorithms that learn representations by minimizing the prediction error of their own future latent representations. Despite its recent empirical success, such algorithms have an apparent defect: trivial representations (such as constants) minimize the prediction error, yet it is obviously undesirable to converge to such solutions. Our central insight is that careful designs of the optimization dynamics are critical to learning meaningful representations. We identify that a faster paced optimization of the predictor and semi-gradient updates on the representation, are crucial to preventing the representation collapse. Then in an idealized setup, we show self-predictive learning dynamics carries out spectral decomposition on the state transition matrix, effectively capturing information of the transition dynamics. Building on the theoretical insights, we propose bidirectional self-predictive learning, a novel self-predictive algorithm that learns two representations simultaneously. We examine the robustness of our theoretical insights with a number of small-scale experiments and showcase the promise of the novel representation learning algorithm with large-scale experiments.

Recent work has shown that machine learning (ML) models can be trained to accurately forecast the dynamics of unknown chaotic dynamical systems. Such ML models can be used to produce both short-term predictions of the state evolution and long-term predictions of the statistical patterns of the dynamics (``climate''). Both of these tasks can be accomplished by employing a feedback loop, whereby the model is trained to predict forward one time step, then the trained model is iterated for multiple time steps with its output used as the input. In the absence of mitigating techniques, however, this technique can result in artificially rapid error growth, leading to inaccurate predictions and/or climate instability. In this article, we systematically examine the technique of adding noise to the ML model input during training as a means to promote stability and improve prediction accuracy. Furthermore, we introduce Linearized Multi-Noise Training (LMNT), a regularization technique that deterministically approximates the effect of many small, independent noise realizations added to the model input during training. Our case study uses reservoir computing, a machine-learning method using recurrent neural networks, to predict the spatiotemporal chaotic Kuramoto-Sivashinsky equation. We find that reservoir computers trained with noise or with LMNT produce climate predictions that appear to be indefinitely stable and have a climate very similar to the true system, while reservoir computers trained without regularization are unstable. Compared with other types of regularization that yield stability in some cases, we find that both short-term and climate predictions from reservoir computers trained with noise or with LMNT are substantially more accurate. Finally, we show that the deterministic aspect of our LMNT regularization facilitates fast hyperparameter tuning when compared to training with noise.

移动网络第五代（5G）的能源消耗是电信行业的主要关注点之一。但是，目前没有一种评估5G基站（BSS）功耗的准确且可进行的方法。在本文中，我们提出了一个新颖的模型，以实现5G多载波BSS功耗的现实表征，该模型以大型数据收集活动为基础。首先，我们定义了允许对多个5G BS产品进行建模的机器学习体系结构。然后，我们利用该框架收集的知识来得出一个现实且可分析的功耗模型，这可以帮助推动理论分析以及功能标准化，开发和优化框架。值得注意的是，我们证明了这种模型具有很高的精度，并且能够捕获节能机制的好处。我们认为，该分析模型是理解5G BSS功耗的基本工具，并准确地优化了网络能源效率。

逆运动学（IK）系统通常相对于其输入特征很僵硬，因此需要将用户干预适应新骨架。在本文中，我们旨在创建一个适用于各种人类形态的灵活的，学到的IK求解器。我们扩展了最先进的机器学习IK求解器，以在众所周知的皮肤多人线性模型（SMPL）上运行。我们称我们的模型SMPL-IK，并表明当集成到实时3D软件中时，该扩展系统为定义新型AI-Asissist Animation Workfrows提供了机会。例如，通过允许用户在摆姿势的同时修改性别和身体形状，可以使姿势创作更加灵活。此外，当使用现有姿势估计算法链接时，SMPL-IK通过允许用户从2D图像引导3D场景来加速摆姿势，同时允许进一步编辑。最后，我们提出了一种新颖的SMPL形状反转机制（SMPL-SI），将任意类人形特征映射到SMPL空间，使艺术家能够在自定义字符上利用SMPL-IK。除了显示拟议工具的定性演示外，我们还介绍了H36M和Amass数据集上的定量SMPL-IK基准。

在过去的十年中，神经网络在使用和研究中发生了爆炸，尤其是在计算机视觉和自然语言处理领域。但是，直到最近，神经网络的进步才能超出狭窄的应用程序的性能改进，并转化为扩展的多任务模型，能够跨多种数据类型和模式概括。同时，已经表明，神经网络被过度参数化为高度，并且修剪技术已被证明能够显着减少网络中的主动权重的数量，同时在很大程度上保留性能。在这项工作中，我们确定了一种方法和网络表示结构，该结构允许修剪的网络使用以前未使用的权重来学习后续任务。我们在众所周知的基准测试数据集上采用这些方法来进行测试目的，并表明使用我们的方法训练的网络能够学习多个任务，这些任务可能是相关或无关的，并在不牺牲任何任务或表现出灾难性遗忘的情况下并行或顺序不相关的。 。

我们为视频建模提供了一个框架，该框架基于deo的扩散概率模型，该模型在各种现实的环境中产生长期视频完成。我们介绍了一个生成模型，该模型可以在测试时间样本中任何任意子集的视频帧的任何任意子集，该视频框架以其他任何子集为条件，并为此提供了适合此目的的体系结构。这样做可以使我们有效地比较和优化各种时间表，以对长视频中的帧进行采样，并在先前采样的帧上使用选择性稀疏和长距离调节。我们证明了对许多数据集的先前工作的改进的视频建模，并在25分钟内进行了临时连贯的视频。我们还根据Carla自动驾驶汽车模拟器中生成的视频发布了一个新的视频建模数据集和语义上有意义的指标。

我们表明，如果基于深度学习的插值器使用球形线性插值器作为基线，可以更准确，有效地求解在一组关键帧上进行人类运动的任务。我们从经验上证明了我们在实现最新性能的公开数据集上的方法的实力。我们通过证明$ \ delta $ - 优势相对于最后已知帧（也称为零速度模型）的参考，进一步概括了这些结果。这支持了一个更一般的结论，即在参考框架本地对输入帧的工作比以前的工作中主张的全球（世界）参考框架更准确，更强大。我们的代码可在https://github.com/boreshkinai/delta-interpolator上公开获取。